{"id":130,"date":"2025-11-18T08:16:56","date_gmt":"2025-11-18T16:16:56","guid":{"rendered":"https:\/\/insidemultisite.salk.edu\/spring-2026\/?page_id=130"},"modified":"2026-03-05T10:40:30","modified_gmt":"2026-03-05T18:40:30","slug":"discoveries","status":"publish","type":"page","link":"https:\/\/inside.salk.edu\/fall-2026\/discoveries\/","title":{"rendered":"Discoveries"},"content":{"rendered":"\n<div data-id=\"a7f18eef\" class=\"wp-block-blocksy-query\"><div class=\"ct-query-template-default is-layout-flow\"><article class=\"wp-block-post is-layout-flow post-1173 post type-post status-publish format-standard has-post-thumbnail hentry category-biochemistry-physics category-discoveries category-discoveries-home\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/visualizing-cellular-life-with-greater-precision\/\">Visualizing cellular life with greater precision<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">August 8, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers have watched viruses infect cells in real time, observed cellular waste collection, and tracked the signaling that\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-1151 post type-post status-publish format-standard hentry category-discoveries category-metabolism\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/an-internal-liver-clock-orchestrates-fat-secretion\/\">An internal liver clock orchestrates fat secretion<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">August 8, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is among the most common chronic liver diseases and, when untreated, can progress to cancer, cardiovascular disease, and diabetes. A new study led by Ronald Evans, PhD, found that production of the protein FGF1\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-1146 post type-post status-publish format-standard hentry category-discoveries category-metabolism\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/how-do-glp-1-drugs-affect-gene-expression\/\">How do GLP-1 drugs affect gene expression?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">August 8, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>GLP-1s are building a reputation as \u201cwonder drugs.\u201d First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health. In addition to those bonus benefits, GLP-1\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-491 post type-post status-publish format-standard has-post-thumbnail hentry category-discoveries category-discoveries-home category-metabolism\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/mitochondrial-dna-can-impact-human-health-and-disease\/\">Mitochondrial DNA can impact human health and disease<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">April 9, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship\u2014but mitochondria brought some baggage. Mitochondria brought their own DNA with them when they\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-489 post type-post status-publish format-standard hentry category-discoveries category-immunobiology\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/why-does-the-body-deem-some-foods-safe-and-others-unsafe\/\">Why does the body deem some foods safe and others unsafe?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">April 9, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>In little moments like when sipping coffee or licking an ice cream cone, it doesn\u2019t seem like your body is pulling off a biological miracle. But it is. That ice cream is not you\u2014yet when you put it in your\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-487 post type-post status-publish format-standard hentry category-discoveries category-plant-biology\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/should-younger-and-older-people-receive-different-treatments-for-the-same-infection\/\">How do plant roots grow in unpredictable temperatures?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">April 9, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Plants can\u2019t move to escape the heat like humans can\u2014they are forced to adapt. As temperatures fluctuate, one key survival strategy is the ability of roots to keep growing, allowing plants to access water and nutrients farther away in the\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-481 post type-post status-publish format-standard has-post-thumbnail hentry category-discoveries category-discoveries-home category-immunobiology\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/can-naked-mole-rats-peacefully-hand-over-power\/\">Can naked mole rats peacefully hand over power?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">April 9, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Naked mole rats keep kingdoms underground. One queen bears all the children, while other mole rats maintain complex subterranean tunnels, forage for food, take care of newborns, and perform other necessary upkeep. This society hinges on the central pillar of\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-248 post type-post status-publish format-standard has-post-thumbnail hentry category-discoveries category-discoveries-home category-plant-biology\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/what-keeps-thirsty-plants-alive-during-drought\/\">What keeps thirsty plants alive during drought?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">January 27, 2026<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>For more than 25 years, the American Southwest has faced the severe social and economic consequences of a megadrought, including a $1.1 billion agricultural loss in California in 2021 alone. New research led by Joseph Ecker, PhD, provides a roadmap\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-75 post type-post status-publish format-standard hentry category-discoveries category-neuroscience\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/how-do-astrocytes-contribute-to-fragile-x-syndrome\/\">How do astrocytes contribute to fragile X syndrome?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">November 13, 2025<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Its symptoms are broad and highly variable, and there is currently no cure. Existing treatments are limited to medications and therapies to help manage symptoms.\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-73 post type-post status-publish format-standard has-post-thumbnail hentry category-cancer category-discoveries category-discoveries-home\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/from-salk-institute-discovery-to-patient-care-vitamin-d-analog-shuts-down-pancreatic-cancers-shield-in-clinical-trial\/\">From Salk Institute discovery to patient care: Vitamin D analog shuts down pancreatic cancer\u2019s shield in clinical trial<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">November 13, 2025<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>A small clinical trial led by the Dana-Farber Cancer Institute put a Salk Institute idea to the test in patients: that activating the vitamin D receptor can help reshape the protective environment surrounding pancreatic tumors in ways that could make\u2026<\/p>\n<\/div>\n<\/article><article class=\"wp-block-post is-layout-flow post-68 post type-post status-publish format-standard has-post-thumbnail hentry category-discoveries category-discoveries-home category-neuroscience\">\n<h2 class=\"ct-dynamic-data wp-elements-15ef05eba43a29c3d982a2fd5ad1d585\"><a href=\"https:\/\/inside.salk.edu\/fall-2026\/what-changes-happen-in-the-aging-brain\/\">What changes happen in the aging brain?<\/a><\/h2>\n\n<div class=\"ct-dynamic-data wp-elements-7e633c711bb4c4f3f527a309d71b28ce\">November 13, 2025<\/div>\n\n<div class=\"ct-dynamic-data wp-elements-1f0aec3e309c89ca6bfb1a77114f443f\"><p>Neurodegenerative diseases affect more than 57 million people globally. Though scientists know that aging is a major risk factor for neurodegenerative diseases, the mechanisms underlying its impact remain unclear. But a great place to start is epigenetic change\u2014the way small\u2026<\/p>\n<\/div>\n<\/article><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-130","page","type-page","status-publish","hentry"],"blocksy_meta":{"page_structure_type":"type-1","styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":6}},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Discoveries - Inside Salk | Fall 2026<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/inside.salk.edu\/fall-2026\/discoveries\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Discoveries - 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