{"id":23,"date":"2025-11-11T10:42:31","date_gmt":"2025-11-11T18:42:31","guid":{"rendered":"https:\/\/insidemultisite.salk.edu\/spring-2026\/?p=23"},"modified":"2026-04-23T11:44:41","modified_gmt":"2026-04-23T18:44:41","slug":"ankita-chadda-the-mechanics-of-moving-forward","status":"publish","type":"post","link":"https:\/\/inside.salk.edu\/spring-2026\/ankita-chadda-the-mechanics-of-moving-forward\/","title":{"rendered":"Ankita Chadda – The mechanics of moving forward"},"content":{"rendered":"\n

Postdoctoral researcher Ankita Chadda, PhD<\/a>, is enjoying a new sense of security in the lab of Agnieszka Kendrick, PhD<\/a>, at Salk.\u00a0<\/h2>\n\n\n\n
Chadda is studying microscopic cellular motors in Aga Kendrick’s lab.\u00a0<\/summary><\/details>\n\n\n\n

\u201cShe\u2019s very straightforward and very planned, which I like,\u201d Chadda says of her faculty advisor. \u201cWe meet every week to discuss my plan for experiments and troubleshoot any issues that are coming up.\u201d <\/p>\n\n\n\n

Chadda is similar in nature, composed and pragmatic. But \u201cstraightforward\u201d isn\u2019t the word she\u2019d use to describe her journey here. <\/p>\n\n\n\n

Chadda grew up in Northwestern India in the rugged landscape of the Thar Desert. \u201cI lived between camels and sand dunes,\u201d she says. \u201cIt was a small town, and very, very dry.\u201d <\/p>\n\n\n\n

Her parents were both doctors and assumed she would follow in their footsteps, but Chadda was cautious about joining the family practice. <\/p>\n\n\n\n

\u201cMy father was a psychiatrist, so there were always patients visiting the house, and that was hard to see at times,\u201d she says. \u201cBut it did make me curious about the human mind and body and interested to understand what goes on inside us on a biochemical level.\u201d <\/p>\n\n\n\n

Chadda studied biology in college but didn\u2019t have a clear plan for her career yet. In the years that followed, her personal life took the reins instead. <\/p>\n\n\n\n

\u201cI moved to South India with my husband, who was also in science,\u201d says Chadda. \u201cAfter that, we moved to Japan, and that\u2019s when I became more exposed to research.\u201d <\/p>\n\n\n\n

Chadda, who was by then also a mother, got a job as a laboratory technician, preparing the necessary samples and tools to help the other scientists carry out their experiments. <\/p>\n\n\n\n

\"\"
An artistic interpretation of dynein complexes (blue, green, and yellow) carrying cargo while traveling along microtubule roads.<\/figcaption><\/figure>\n\n\n\n

When she relocated to the US, she was prepared to take on a similar role at the University of Iowa. But working in a smaller lab, Chadda soon found herself doing more than the typical technician. <\/p>\n\n\n\n

\u201cWe didn\u2019t have enough funding to hire more people, so the professor asked me to get more involved in the research,\u201d she says. \u201cI suddenly had the opportunity to do my own experiments, and I eventually got to publish a paper about my findings.\u201d <\/p>\n\n\n\n

This was a critical moment in Chadda\u2019s self-discovery. For the first time, she was able to really see herself as a scientist. She had her own research questions, she was planning her own experiments, and she was ready for more. <\/p>\n\n\n\n

\u201cMost people go to graduate school right after college, but I had this 15-year gap,\u201d she says. \u201cI finally decided, though, \u2018If I want to keep doing my science, I will have to get a PhD.\u2019\u201d <\/p>\n\n\n\n

In 2018, Chadda made her biggest move yet. She left for St. Louis to start a PhD program in the Biochemistry and Molecular Biophysics department at Washington University. <\/p>\n\n\n\n

Over the next several years, Chadda dove deep into the world of protein mechanics. These skills led her to Kendrick\u2019s lab at Salk, where she now studies motor proteins, tiny molecular machines that work like delivery trucks to transport cargo throughout our cells. She\u2019s currently exploring the structure and function of dynein, a motor protein that plays an important role in brain health. <\/p>\n\n\n\n

Dynein is responsible for transporting cargo from the outer edges of a cell back toward its central nucleus. In some extra-long nerve cells, this journey can be up to a meter long. So how does the cell ensure each package gets sent in the right direction? <\/p>\n\n\n\n

Using cutting-edge cryo-electron microscopy, Chadda is filming dynein in action, capturing the tiny delivery truck in near-atomic resolution. The footage is revealing exactly how dynein interacts with other molecules to grab the right package and begin its journey back to the nucleus. The more we understand the mechanics of this process, the more smoothly we can keep it running as we age. <\/p>\n\n\n\n

Onward and upward <\/h3>\n\n\n\n
\"\"<\/figure>\n\n\n\n

Dynein may be traveling backward, but Chadda continues to move forward. <\/p>\n\n\n\n

As a postdoctoral researcher at Salk, Chadda has more scientific freedom than ever before. She designs her own experiments, manages collaborations across labs, and mentors younger students and technicians. <\/p>\n\n\n\n

But this new autonomy also comes with added pressure. Unlike graduate students, postdoctoral researchers must often secure their own funding. Chadda estimates that applying for fellowships can take 15 or more hours of a postdoctoral researcher’s week. <\/p>\n\n\n\n

That\u2019s why philanthropic support for postdoctoral researchers is so important. Chadda is the inaugural recipient of the La Mer Fellowship in Healthy Aging<\/a>. Through this fellowship, La Mer\u2019s backing makes it possible for Chadda to pursue the foundational questions that move the field forward. <\/p>\n\n\n\n

These days, Chadda is embracing her independence both in and out of the lab, enjoying life in sunny San Diego as her son finishes college back in St. Louis. <\/p>\n\n\n\n

\u201cI wanted him to go into research,\u201d she says with a smile, \u201cbut he\u2019s studying computer science. He\u2019s not sure what he\u2019ll do next, though.\u201d <\/p>\n\n\n\n

If he follows his mother\u2019s brave example, he is sure to find his way forward. <\/p>\n\n\n\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Postdoctoral researcher Ankita Chadda, PhD, is enjoying a new sense of security in the lab of Agnieszka Kendrick, PhD, at Salk.\u00a0 \u201cShe\u2019s very straightforward and very planned, which I like,\u201d Chadda says of her faculty advisor. \u201cWe meet every week to discuss my plan for experiments and troubleshoot any issues that are coming up.\u201d  Chadda […]<\/p>\n","protected":false},"author":3,"featured_media":494,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,11,7],"tags":[],"class_list":["post-23","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-home-hero-slider","category-in-this-issue","category-next-gen"],"blocksy_meta":{"content_style_source":"inherit","content_style":"wide","styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":6}},"yoast_head":"\nAnkita Chadda - The mechanics of moving forward 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