Cancer treatments have long been moving toward personalization—finding the right drugs that work for a patient’s unique tumor, based on specific genetic and molecular patterns. Many of these targeted therapies are highly effective but aren’t available for all cancers, including non-small cell lung cancers (NSCLCs) that have an LKB1 genetic mutation. A new study led by Professor Reuben Shaw and collaborators from Northwestern University revealed FDA-approved trametinib and entinostat (which is currently in clinical trials) can be given in tandem to produce fewer and smaller tumors in mice with LKB1-mutated NSCLC. The findings may lead to clinical trials to test the new regimen in humans.
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Interaction + Infrastructure = Innovations in Healthy AgingSalk formula recalculates aging research, shifting focus to overall resilience and health span.
Professor Jan Karlseder named Salk’s Chief Science OfficerOn February 1, Jan Karlseder started as Salk’s new senior vice president and chief science officer (CSO). 
Salk mourns the loss of Nobel Laureate Roger GuilleminThe Institute remembers the “father of neuroendocrinology” for his many contributions to science and friendship to all.
Daniel Hollern–Turning a cancer diagnosis into a career in basic researchAssistant Professor Daniel Hollern pivoted his career trajectory after a family member’s life-changing diagnosis pushed his already-curious mind off a cliff of questions—starting with, “What can I do to help him?”
Jerry Sheehan–Collaborating shoulder to shoulder with scientistsWhen you think about a person who heads an information technology department, you might not envision them working shoulder to shoulder with research scientists. But that’s exactly the approach Jerry Sheehan is taking as Salk’s new chief information officer (CIO).
Laura Mainz–Taking control after a cancer diagnosisLaura Mainz grew up in a tiny village in midwestern Germany, with just as many cows as people. But the sweeping landscape speckled with farms never swayed her toward plant biology—instead, her interest in the human body grew.
Black Association affinity group cultivates welcoming environmentThe Black Association at Salk (BAS) was one of the first affinity groups formed at Salk in 2020. Since that time, it has established itself as a welcoming space and go-to for resources for all Black Salk community members.