Location, location, location: the cell membrane facilitates RAS protein interactions
Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS. Now, Salk Professor Geoffrey Wahl, first author Yao-Cheng (Leo) Li and a team of scientists have uncovered details of how normal RAS interacts with mutated RAS and other proteins in living cells for the first time. The findings could aid in the development of better RAS-targeted cancer therapeutics.
Featured Stories
- To inspire and educate: Salk’s Education Outreach is on a missionMotivated by Jonas Salk’s admonition to “be good ancestors,” Education Outreach strives to inspire the next generation of scientists. By running programs like the Mobile Science Lab or High School Science Day among others, Education Outreach encourages scientific literacy, enthusiasm in science as a career, and awareness of the value of basic research.
- Deepshika Ramanan–From iguana poop to breastmilkRamanan, a new assistant professor and microbiologist by training, made a chance discovery about animal gut bacteria that led to her fascination with breastmilk immunity.
- New strategic plan provides roadmap for enhancing diversity, equity, inclusion, and belonging at SalkGroundbreaking scientific discoveries require talented people behind the scenes, and the more diverse those people are, the more groundbreaking their discoveries. At Salk, improving diversity, equity, and inclusion is a commitment to both scientific discovery and humanity.
- Trinka Adamson–Supporting Salk science through animal careAdamson, senior director of Salk’s Animal Resources Department, works to provide the highest quality veterinary medical care, husbandry, enrichment, and professional technical support to enable our scientists to conduct their animal research and make their bold discoveries.
- Melissa Hernandez–Horses, hot sauce, and human brain researchHernandez, a postdoctoral researcher in the lab of Professor Rusty Gage, journeyed up and down the west coast and turned from scientist to hot sauce entrepreneur and back before finally settling at Salk to study neuroscience.
Support a legacy where cures begin.
Scientific discovery at the Salk Institute is made possible through your annual contributions. Your support will accelerate the pace of breakthroughs in understanding disease and pave the way to new drug therapies.
Get involved