Healthy Aging
Healthy Aging
Getting older doesn't have to mean getting sicker. We are committed to discovering the fundamental causes of aging and finding new ways to prevent and treat aging-related diseases.

Professor Juan Carlos Izpisua Belmonte, co-first author Hsin-Kai Liao and colleagues developed a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome, a rare genetic disorder that also afflicts humans. The treatment provides insight into the molecular pathways involved in accelerated aging, as well as how gene therapy can be used to reduce toxic proteins.

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