We are rapidly demystifying cancers, exposing the molecular mechanisms underlying tumors and leading the search for the next generation of targeted cancer therapies. We see a future where every cancer and every patient has a cure.
In a study led by Professor Geoffrey Wahl and Vanderbilt Assistant Professor Kathy DelGiorno, first author Zhibo Ma and colleagues found that cells in the pancreas form new cell types to mitigate injury, but then become susceptible to cancerous mutations. Their findings establish a better understanding of the pancreas’ healing mechanisms and offer insights into what happens when the process goes awry. Targeting these processes may lead to new treatments for patients with pancreatitis and pancreatic cancer.

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