We are rapidly demystifying cancers, exposing the molecular mechanisms underlying tumors and leading the search for the next generation of targeted cancer therapies. We see a future where every cancer and every patient has a cure.
Mitochondria are known as the powerhouses of the cell, generating the energy that’s needed to fuel the functions that our cells carry out. Senior Vice President and Chief Science Officer Martin Hetzer, first author Shefali Krishna and colleagues have taken a closer look at how mitochondria are maintained in nondividing cells, such as neurons. The researchers found that many of the proteins in mitochondria last much longer than expected, and that this stability likely protects them from damage. These findings will ultimately help researchers better understand age-related diseases, such as Alzheimer’s disease, and offer insights on treatment and prevention

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