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Salk scientists reveal role of genetic switch in pigmentation and melanoma

Despite only accounting for about 1 percent of skin cancers, melanoma causes the majority of skin cancer-related deaths. While treatments for this serious disease do exist, these drugs can vary in effectiveness depending on the individual. A study by Professor Marc Montminy and Staff Scientist Jelena Ostojić reveals new insights about a protein called CRTC3, a genetic switch that could potentially be targeted to develop new treatments for melanoma by keeping the switch turned off.

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