Salk scientists reveal role of genetic switch in pigmentation and melanoma
Despite only accounting for about 1 percent of skin cancers, melanoma causes the majority of skin cancer-related deaths. While treatments for this serious disease do exist, these drugs can vary in effectiveness depending on the individual. A study by Professor Marc Montminy and Staff Scientist Jelena Ostojić reveals new insights about a protein called CRTC3, a genetic switch that could potentially be targeted to develop new treatments for melanoma by keeping the switch turned off.
- Building a More Resilient WorldThe world is facing an array of health-related crises: COVID-19 and other infectious diseases, climate change, neurodegenerative conditions, cancers and many more. To tackle these daunting challenges, the Institute is embarking on a philanthropic campaign to focus on resilience: the biological adaptability that mitigates the effects of aging, resists disease and restores global wellness.
- Susan Kaech – How T cells rememberSalk Professor Susan Kaech, director of the NOMIS Center for Immunobiology and Microbial Pathogenesis, has made it her mission to gain a better understanding of how T cells form, how they exchange molecular signals with the surrounding tissue, and how we can use this knowledge to prevent or treat infections.
- Carl Procko – Lessons from carnivorous plantsStaff Scientist Carl Procko studies Venus flytraps and their close relatives, Sundew plants, to gain insight into the ultra-fast biochemistry of plants and how they can sense touch. It doesn’t hurt that these bug-eating plants are a great way to get kids—and adults—interested in science.
- Nuttida Rungratsameetaweemana – Drawing from memoriesNuttida Rungratsameetaweemana, a Salk postdoctoral researcher who studies neuroscience, was introduced to the perplexities of the brain at age 14 during a chance encounter in a hospital waiting room.