New technologies are allowing us to explore the brain as never before. We are entering a new era in neuroscience where our knowledge of the brain is beginning to match the urgent need to prevent and treat diseases of the brain.

Professor and co-corresponding author Terrence Sejnowski, along with collaborators at the University of Texas at Austin and the University of Otago, in New Zealand, found that connections in the brain not only expand as needed in response to learning or experiencing new things, but that others shrink as a result. The work could shed light on conditions in which memory formation is impaired, such as depression or Alzheimer’s disease.

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