Professor Joseph Ecker, along with co-first authors Florian Jupe, Angeline Rivkin, Mark Zander and Todd Michael (of the J. Craig Venter Institute) and colleagues mapped the genomes and epigenomes of genetically modified plant lines with high resolution to show what happens at a molecular level when a piece of foreign DNA is inserted. Their findings not only elucidate the routine methods used to modify plants but also offer new ways to minimize potential off-target effects.Read News Release
To repair DNA damage, plants need good contractors
Associate Professor Julie Law and first author Clara Bourbousse showed which genes are turned on or off, and in which order, to protect and repair the genome in response to DNA damage.
The research reveals the genetic framework controlling a complex biological process that has broad implications for understanding how plants in particular, and organisms in general, cope with DNA damage to ensure long-term health and fitness.Read News Release
- Gerald Shadel explores stressed-out mitochondriaInside Salk sat down with Shadel to find out how he became interested in mitochondria, what he is driven by scientifically and what he has learned about aging along the way.
- The science of agingWhat we know about longevity so far: Minimizing smoking, obesity and overeating while maximizing exercise and social interactions seem to correspond to longer and healthier lives, but not always. While many factors have been touted as panaceas for extending life–everything from adhering to a Mediterranean diet to regularly imbibing red wine–a “fountain of youth” has remained stubbornly elusive.
- Lillian Eichner: Reading the clues to fight cancerEichner began studying cancer while pursuing her PhD at McGill University in Montreal. She was drawn to the Salk Institute for her postdoctoral studies because Reuben Shaw, director of the Salk Cancer Center and a professor in Salk’s Molecular and Cell Biology Laboratory, has taken a new approach to cancer by studying the metabolic pathways of deadly tumors.