Anti-inflammatory molecules that decline in the aging brain
Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolic changes, and many others. Professor Alan Saghatelian, Senior Research Associate Dan Tan, and colleagues, in collaboration with UC San Diego, revealed another factor implicated in the aging process—a class of lipids called SGDGs, which decline in the brain with age and may have anti-inflammatory effects. The finding could have implications for neurodegenerative disorders and other conditions that involve increased brain inflammation.
Nature Chemical Biology
10/2022
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