First immune-evading cells created to treat type 1 diabetes
Professor Ronald Evans, first author and former Staff Scientist Eiji Yoshihara, and colleagues have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes. Using stem-cell technology, they generated the first human insulin-producing pancreatic cell clusters able to evade the immune system. These “immune shielded” cell clusters controlled blood glucose without immunosuppressive drugs in mice, once transplanted in the body.
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