In research that aims to illuminate the causes of human developmental disorders, Professor Joseph Ecker, first author Yupeng He, and colleagues have generated 168 new maps of chemical marks on strands of DNA—called methylation—in developing mice. The data can help narrow down regions of the human genome that play roles in diseases such as schizophrenia and Rett syndrome.
How cells solve their identity crisis
Cancer is often the result of DNA mutations or problems with how cells divide, which can lead to cells “forgetting” what type of cell they are or how to function properly. Professor and VP/CSO Martin Hetzer, first author Hyeseon Kang, Assistant Professor Jesse Dixon and colleagues have now provided clarity into how new cells remember their identity after cell division. These memory mechanisms could explicate problems that occur when cell identity is not maintained, such as cancer.Read News Release
- Leading Salk science into the futureInside Salk sat down with Rusty Gage to learn more about his background, approach to managing a world-renowned Institute, and vision for Salk science over the next decade.
- Julie Law – Revealing RNAAssociate Professor Julie Law shares common themes underlying her research and discusses what motivates her both in and out of the lab.
- Gerald Pao – Pushing the limits in science and lifeFrom studying the novel coronavirus to downloading brains to computers, Staff Scientist Gerald Pao is at the forefront of scientific advancement.
- Austin ColeyAustin Coley, though only at Salk since 2019, has already taken an active role in everything from conducting innovative research on the brain to spearheading a wide variety of outreach activities.
- Salk’s Harnessing Plants Initiative (HPI) Garners Widespread SupportNew grants are supporting the Institute’s efforts to optimize plants’ natural ability to store carbon and mitigate climate change. This support bolsters the ongoing HPI project focused on model plants that was funded through donations to The Audacious Project in 2019.