New maps of chemical marks on DNA pinpoint regions relevant to many developmental diseases
In research that aims to illuminate the causes of human developmental disorders, Professor Joseph Ecker, first author Yupeng He, and colleagues have generated 168 new maps of chemical marks on strands of DNA—called methylation—in developing mice. The data can help narrow down regions of the human genome that play roles in diseases such as schizophrenia and Rett syndrome.
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